What are enzyme detergent cleaners?

Four types of enzymes working with surface cleaning detergents achieve superior intraocular eye surgical instrument cleaning.

Eye surgical instrument cleaning detergents that do not contain four enzymes cannot remove all forms of surgical debris. The applications for those enzymes are: lipase enzyme cleaners to remove fat, amylase enzymes to remove starch, carbohydrase enzymes to remove high starches, and protease enzymes to remove blood and lipids emulsified with proteins. The bioburden of emulsified lipids with proteins, which need to be removed from phacoemulsification handpieces, is cleaned by the highly concentrated ONEcleaner eye surgical instrument cleaning solutions.

Enzymes are not used up in a single cleaning reaction so they are available to for more cleaning. The cleaning performance of enzymes continues cleaning but declines if they are overwhelmed by the volume of debris.

One type of enzyme is able to break down a specific type of debris, like a lock fits a key. The active site of an enzyme can only react to a specific type of debris. If the type of enzyme does not match the type of debris, no cleaning occurs. Specific types of enzymes are needed for effective cleaning the types of debris found on soiled intraocular eye surgical instruments, debris such as proteins (blood,) lipids, and starches.

Proteins emulsified with lipids are encountered when cleaning phacoemulsification handpieces. This presents a significant cleaning challenge. Highly concentrated lipase with protease enzymes offer the highest probability of superior cleaning outcomes, for residue free intraocular eye surgical instruments.

eye surgical instrument cleaners

Lipase Enzymes: break down fats to cleave fatty acid residue from the glycerol residue in a neutral fat or a phospholipid.
Amylase Enzymes: break down starches to catalyze the hydrolysis of starch to sugar to produce carbohydrate derivatives.
Carbohydrase Enzymes: break down starch to a lower levels to catalyze the hydrolysis of higher carbohydrates to lower forms.
Protease Enzymes: break down blood including the proteinases and peptidases, to catalyze the hydrolytic break down of proteins.

enzymatic eye surgical instrument cleaners

Common misunderstandings exist pertaining to the use of enzymes and detergents, including the times and temperatures that render the optimal cleaning outcomes.

The use of the optimal cleaning times and temperatures will render a higher probability of superior cleaning outcomes.

optimal enzyme temperatures for
eye surgical instrument cleaners

The temperature for optimal enzyme cleaning performance peaks at 137 degrees Fahrenheit (58.33 degree Celsius). The cleaning activity of the enzyme at temperatures below and above this point is less but cleaning does occur. The cleaning activity of the enzyme does not stop at this peak temperature but is does lessen as the temperature increases or decreases. Given the range of water temperatures available, and used, for cleaning intraocular eye surgical instruments, the temperatures do not impact the cleaning performance of detergents.

cleaning eye surgical instruments
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